private Map factories = new HashMap<Object, org.springframework.amqp.rabbit.connection.ConnectionFactory>(2);
....
@PostConstruct
    public void init(){
        factories.put("foo", defaultCachingConnectionFactory());
        factories.put("bar", connectionFactory2());
    }
....
@Bean
    public ConnectionFactory defaultCachingConnectionFactory() {

        CachingConnectionFactory connectionFactory = new CachingConnectionFactory();
        connectionFactory.setHost(host);
        connectionFactory.setUsername(user);
        connectionFactory.setPassword(password);
        connectionFactory.setConnectionTimeout(timeOut);
        connectionFactory.setRequestedHeartBeat(heartBeat);
        return connectionFactory;
    }
....
        SimpleRoutingConnectionFactory one = new SimpleRoutingConnectionFactory();
        one.setTargetConnectionFactories(factories);
....

java.lang.IllegalStateException: Cannot determine target ConnectionFactory for lookup key [null]
	at org.springframework.amqp.rabbit.connection.AbstractRoutingConnectionFactory.determineTargetConnectionFactory

rabbitTemplate.sendAndReceive(HOST, exchange, routingKey, message);