Вот кусок из документации:

Use the --skip-external-locking MySQL option to avoid external locking. This option is on by default as of MySQL 4.0. Before that, it is on by default when compiling with MIT-pthreads, because flock() isn't fully supported by MIT-pthreads on all platforms. It's also on by default for Linux because Linux file locking is not yet safe. Note that the --skip-external-locking option will not affect MySQL's functionality as long as you run only one server. Just remember to take down the server (or lock and flush the relevant tables) before you run myisamchk. On some systems this option is mandatory, because the external locking does not work in any case. The only case when you can't use --skip-external-locking is if you run multiple MySQL servers (not clients) on the same data, or if you run myisamchk to check (not repair) a table without telling the server to flush and lock the tables first. You can still use LOCK TABLES and UNLOCK


Так что вроде можно. надо только этот --skip-external-locking отключить (раз он по умолчанию)