use master
    CREATE MASTER KEY ENCRYPTION BY PASSWORD = 'Некоторый пароль'  
    

use master
GO
CREATE ASYMMETRIC KEY CLR_SP_Key
FROM EXECUTABLE FILE = 'D:\t\MyCLR.dll'
GO 

use master
CREATE LOGIN CLR_SP_Login FROM ASYMMETRIC KEY CLR_SP_Key

use myBase
CREATE USER CLR_SP_user FOR LOGIN CLR_SP_Login

use myBase
CREATE ASSEMBLY SQLCLR_REGEX  FROM 'D:\t\MyCLR.dll'
with permission_set=SAFE;  
go

Msg 10343, Level 14, State 1, Line 20
CREATE or ALTER ASSEMBLY for assembly 'CLR_Regex_Functions' with the SAFE or EXTERNAL_ACCESS option failed because the 'clr strict security' option of sp_configure is set to 1. Microsoft recommends that you sign the assembly with a certificate or asymmetric key that has a corresponding login with UNSAFE ASSEMBLY permission. Alternatively, you can trust the assembly using sp_add_trusted_assembly.

use master
grant UNSAFE ASSEMBLY to CLR_SP_Login