MasterZiv,
Похоже, что да, но должно быть открыто по крайней мере одно win-приложение:
Отсюда: http://forum.winehq.org/viewtopic.php?t=766
vitamin@WineHQ Forums
Install it properly (so it installs itself as a service) then run it with 'net start <service_name>'. Of course make sure you have some other app running under Wine, like notepad. Or your service will be killed 5 seconds after start.


vitamin@WineHQ Forums
Maybe in some distant future it would be ok to run Wine in the background all the time. But not now.
For now the only realm where Wine used is user programs. Any services that must run all the time have to have a native Linux version. Request such software from your vendor. Or switch to vendor that provides native Linux versions.
You can always start a separate program such as notepad and keep it running. This will keep your services up and running.