using CsvHelper;
using System;
using System.Collections.Generic;
using System.Drawing;
using System.IO;
using System.Windows.Forms;
using System.Drawing.Imaging;

namespace ColorTest
{
    public partial class Form1 : Form
    {
        Image image; //Изображение
        Int32 WidthPicture = 6;  //Ширина фрагмента картинки
        Int32 HeightPicture = 6; //Высота фрагмента картинки

        List<Data_ForGrayscale> List_data_ForGrayscale; // List для данных с оттенками серого
        List<Data_ForRGB> List_data_ForRGB; //List для данных с RGB        

        public Form1()
        {
            InitializeComponent();
        }

        private void Form1_Load(object sender, EventArgs e)
        {
            image = Image.FromFile("C:\\Users\\Acer\\Desktop\\image1.jpg");
            pictureBox1.Image = image;

            List_data_ForGrayscale = new List<Data_ForGrayscale>();
            List_data_ForRGB = new List<Data_ForRGB>();
        }

        private void pictureBox1_MouseDown(object sender, MouseEventArgs e)
        {

            if (e.X - WidthPicture/2 >= 0 &&                //Чтобы не выходили за край PictureBox
                e.Y - HeightPicture/2 >= 0 &&               // с учетом ширины и высоты фрагмента
                e.X + WidthPicture/2 < pictureBox1.Width && //
                e.Y + HeightPicture/2 < pictureBox1.Height) //
            {
                Data_ForGrayscale CurrentData_ForGrayscale = new Data_ForGrayscale(WidthPicture * HeightPicture);
                Data_ForRGB CurrentData_ForRGB = new Data_ForRGB(WidthPicture * HeightPicture);

                Rectangle cloneRect = new Rectangle((int)e.X - WidthPicture/2,
                                                    (int)e.Y - HeightPicture/2,
                                                    WidthPicture,
                                                    HeightPicture);                

                Bitmap myBitmap = new Bitmap(image);
                PixelFormat pixelformat = myBitmap.PixelFormat;
                Bitmap cloneBitmap = myBitmap.Clone(cloneRect, pixelformat); //Получаем фрагмент

                Color pixelColor;

                int numberPixel = -1;

                for (int i = 0; i < WidthPicture; i++)
                {
                    for (int j = 0; j < HeightPicture; j++)
                    {
                        pixelColor = cloneBitmap.GetPixel(i, j);

                        numberPixel = numberPixel + 1;
                        CurrentData_ForGrayscale.Grayscale[numberPixel] = 255 - Convert.ToInt32(pixelColor.R * 0.2126 + 
                                                                                                pixelColor.G * 0.7152 + 
                                                                                                pixelColor.B * 0.0722);
                        CurrentData_ForGrayscale.Marker = 1;
                        
                        CurrentData_ForRGB.ColorRGB[numberPixel].ColorR = pixelColor.R;
                        CurrentData_ForRGB.ColorRGB[numberPixel].ColorG = pixelColor.G;
                        CurrentData_ForRGB.ColorRGB[numberPixel].ColorB = pixelColor.B;
                        CurrentData_ForRGB.Marker = 1;
                    }
                }

                List_data_ForGrayscale.Add(CurrentData_ForGrayscale);
                List_data_ForRGB.Add(CurrentData_ForRGB);
            }

        }

        private void button_Save_Click(object sender, EventArgs e)
        {
            //Сохраняем в CSV-файл с оттенками серого
            string pathCsvFileForGrayscale = "C:\\Users\\Acer\\Desktop\\Marker1.csv";            

            using (StreamWriter streamReader = new StreamWriter(pathCsvFileForGrayscale, true))
            {
                using (CsvWriter csvReader = new CsvWriter(streamReader))                
                {
                    csvReader.Configuration.HasHeaderRecord = false;
                    //csvReader.Flush();                    
                    csvReader.Configuration.Delimiter = ",";                    
                    for (int i = 0; i < List_data_ForGrayscale.Count; i++)
                    {
                        csvReader.WriteField(List_data_ForGrayscale[i].Marker);

                        for (int j = 0; j < List_data_ForGrayscale[i].Grayscale.Length; j++)
                        {
                            csvReader.WriteField(List_data_ForGrayscale[i].Grayscale[j]);
                        }
                        csvReader.NextRecord();
                    }
                }
            }

            List_data_ForGrayscale = new List<Data_ForGrayscale>();

            //Сохраняем в CSV-файл с RGB
            string pathCsvFileForGRB = "C:\\Users\\Acer\\Desktop\\Marker2.csv";

            using (StreamWriter streamReader = new StreamWriter(pathCsvFileForGRB, true))
            {
                using (CsvWriter csvReader = new CsvWriter(streamReader))
                {
                    csvReader.Configuration.HasHeaderRecord = false;                    
                    //csvReader.Flush();                    
                    csvReader.Configuration.Delimiter = ",";
                    for (int i = 0; i < List_data_ForRGB.Count; i++)
                    {
                        csvReader.WriteField(List_data_ForRGB[i].Marker);

                        for (int j = 0; j < List_data_ForRGB[i].ColorRGB.Length; j++)
                        {
                            var colorRGB= List_data_ForRGB[i].ColorRGB[j];                            
                            var output = "[" +
                                                colorRGB.ColorR.ToString() + ";" + 
                                                colorRGB.ColorG.ToString() + ";" + 
                                                colorRGB.ColorB.ToString() + "]";
                            csvReader.WriteField(output);
                        }
                        csvReader.NextRecord();
                    }                    
                }
                List_data_ForRGB = new List<Data_ForRGB>();
            }
        }        
    }

using System;
using System.Collections.Generic;
using System.Drawing;
using System.IO;
using System.Windows.Forms;
using System.Drawing.Imaging;
using System.Runtime.Serialization.Json;

namespace ColorTest
{
    public partial class Form1 : Form
    {
        Image image; //Изображение
        Int32 WidthPicture = 6;  //Ширина фрагмента картинки
        Int32 HeightPicture = 6; //Высота фрагмента картинки

        List<Data_Color> List_dataColor; // List для данных Color        

        public Form1()
        {
            InitializeComponent();
        }

        private void Form1_Load(object sender, EventArgs e)
        {
            image = Image.FromFile("C:\\Users\\Acer\\Desktop\\image1.jpg");
            pictureBox1.Image = image;

            List_dataColor = new List<Data_Color>();            
        }

        private void pictureBox1_MouseDown(object sender, MouseEventArgs e)
        {

            if (e.X - WidthPicture/2 >= 0 &&                //Чтобы не выходили за край PictureBox
                e.Y - HeightPicture/2 >= 0 &&               // с учетом ширины и высоты фрагмента
                e.X + WidthPicture/2 < pictureBox1.Width && //
                e.Y + HeightPicture/2 < pictureBox1.Height) //
            {
                Data_Color CurrentDataColor = new Data_Color(WidthPicture * HeightPicture);                

                Rectangle cloneRect = new Rectangle((int)e.X - WidthPicture/2,
                                                    (int)e.Y - HeightPicture/2,
                                                    WidthPicture,
                                                    HeightPicture);                

                Bitmap myBitmap = new Bitmap(image);
                PixelFormat pixelformat = myBitmap.PixelFormat;
                Bitmap cloneBitmap = myBitmap.Clone(cloneRect, pixelformat); //Получаем фрагмент

                Color pixelColor;

                int numberPixel = -1;

                for (int i = 0; i < WidthPicture; i++)
                {
                    for (int j = 0; j < HeightPicture; j++)
                    {
                        pixelColor = cloneBitmap.GetPixel(i, j);

                        numberPixel = numberPixel + 1;
                        CurrentDataColor.Color[numberPixel] = pixelColor;                        
                    }
                }

                CurrentDataColor.Marker = 1;
                CurrentDataColor.GetColorGrayscale();

                List_dataColor.Add(CurrentDataColor);                
            }

        }

        private void button_Save_Click(object sender, EventArgs e)
        {
            string pathjson = "C:\\Users\\Acer\\Desktop\\Marker2.json";

            var jsonFormatter = new DataContractJsonSerializer(typeof(List<Data_Color>));

            /*using (var file = new FileStream(pathjson, FileMode.Append))
            {
                jsonFormatter.WriteObject(file, List_dataColor);
            }*/

            List<Data_Color> oldList;

            try
            {
                using (var fs = new FileStream(pathjson, FileMode.Open))
                {
                    oldList = jsonFormatter.ReadObject(fs) as List<Data_Color>;
                }                
            }
            catch (Exception ex)
            {
                oldList = new List<Data_Color>();
            }

            foreach (Data_Color data_color in List_dataColor)
            {
                oldList.Add(data_color);
            }

            using (var file = new FileStream(pathjson, FileMode.OpenOrCreate))
            {
                jsonFormatter.WriteObject(file, oldList);
            }

            List_dataColor = new List<Data_Color>();
        }        
    }
}