var sOutput = validateFile("e.xml");
var FSO = WScript.CreateObject("Scripting.FileSystemObject");
var FLog = FSO.OpenTextFile("result.txt", 8 ,true);
FLog.WriteLine(sOutput);
FLog.Close();

function validateFile(strFile)
{
    var xs = new ActiveXObject("MSXML2.XMLSchemaCache.4.0");
    xs.add("http://www.editeur.org/onix/2.1/reference", "ONIX_BookProduct_Release2.1_reference.xsd");

    var xd = new ActiveXObject("MSXML2.DOMDocument.4.0");
    xd.schemas = xs;
    xd.async = false;
    xd.validateOnParse = true;
    xd.resolveExternals = true;
    xd.load(strFile);
    if (xd.parseError.errorCode !=  0 )
    {
         return("Validation failed on " + strFile + 
                "\n=====================" +
                "\nReason: " + xd.parseError.reason + 
                "\nSource: " + xd.parseError.srcText + 
                "\nLine: " + xd.parseError.line + "\n");
    }
    else 
         return("Validation succeeded for " + strFile + 
                "\n======================\n" +"\n");
}

<?xml version="1.0" encoding="UTF-8"?>
<ONIXMessage xmlns="http://www.editeur.org/onix/2.1/reference" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.editeur.org/onix/2.1/reference
http://www.editeur.org/onix/2.1/reference/ONIX_BookProduct_Release2.1_reference.xsd">