Excel.Worksheet Sheet = (Excel.Worksheet)Sheets.get_Item(1);

try
            {
                xlsApplication = new Excel.Application();

                xlsApplication.Visible = true;
                Excel.Workbook xlsWorkbook = xlsApplication.Workbooks.Open("C:\\Work\\Номенклатура.xls", Type.Missing, Type.Missing, Type.Missing, Type.Missing, Type.Missing, Type.Missing, Type.Missing, Type.Missing, Type.Missing, Type.Missing, Type.Missing, Type.Missing, Type.Missing, Type.Missing);
                Excel.Sheets Sheets = xlsWorkbook.Worksheets;
                Excel.Worksheet Sheet = (Excel.Worksheet)Sheets.get_Item(1);

            }
            catch (Exception err)
            {
                MessageBox.Show(err.Message);
            }
            finally
            {
                xlsApplication.Quit();
            }